There are reports that Viagra can cause sperm damage in extremely rare cases, but the chances of this happening are minimal. In fact, Viagra is much more likely to positively affect fertility, as it helps men achieve and maintain an erection. Sildenafil is a potent and selective inhibitor of the PDE type 5 enzyme specific to cyclic guanosine monophosphate (cGMP) and therefore improves the activity of the nitric oxide-cGMP pathway that promotes penile erection. The drug is relatively lipophilic (log D7.4 %3D 2) and is therefore expected to be distributed in seminal fluid. Men with erectile dysfunction are likely to use sildenafil as an aid to procreation, especially in younger patients who have erectile dysfunction secondary to spinal cord injury.
Because of this, a clinical study was conducted to investigate the effect of a single oral dose of sildenafil on several parameters of semen and sperm motility and morphology. In addition, the concentrations of sildenafil and its main circulating metabolite (UK-103,320) were measured in semen samples and compared with those obtained in plasma. Researchers have warned that the use of Viagra may harm men's fertility. Experiments suggest that the drug against impotence may damage sperm and prevent some men from having families. Sildenafil (Viagra), tadalafil (Cialis), and vardenafil (Levitra) are commonly prescribed for the treatment of erectile dysfunction in men.
Here's what you need to know about male enhancement pills and male fertility, including common ingredients in erectile dysfunction supplements that can be harmful and which are safe for sperm. However, the potential side benefits of erectile dysfunction medications on male fertility have not yet been studied in detail. Because some people have difficulty conceiving as a result of erectile or orgasmic dysfunction, male enhancement pills can help, as they allow a couple to have sex and ejaculate. The researchers also found that chronic administration of medications for erectile dysfunction appeared to be more effective in improving sperm parameters than simply taking the pills as needed. In clinical trials, sildenafil has been shown to increase the duration and stiffness of penile erection in response to visual sexual stimuli in a hospital setting and greatly improves the ability to achieve erections, leading to the successful completion of sexual intercourse at home. People use male enhancement pills to treat low libido, low sexual stamina, or erectile dysfunction. After analyzing the numbers from 11 studies involving 1,317 men, they found that taking medications for erectile dysfunction increased the number of motile sperm and normally shaped sperm in men who were considered infertile due to low sperm counts, for example. According to researchers, by blocking PDE5, erectile dysfunction medications may increase the effects of a chemical substance in the body called cyclic guanosine monophosphate, or cGMP, which is important for sperm motility and fertilization.
In addition, the FDA has discovered that several sexual enhancement supplements that are marketed as “herbal” or “natural” actually contain sildenafil or other active ingredients from prescription drugs for erectile dysfunction. Often labeled as dietary supplements, male enhancement pills claim to increase sexual performance by increasing testosterone levels, improving erections, improving libido, and more. Male enhancement pills are supposed to increase blood flow to the penis to help users obtain and maintain an erection, increasing sexual desire and performance. If you're considering taking a male enhancement pill to improve sexual desire or performance, pay attention to the ingredients to avoid potential harmful effects on fertility and choose a legitimate manufacturer (avoid those on the FDA's bad list).